Chemical Biology in Drug Discovery: Visualizing Biological Processes

  • Core techniques in chemical biology
  • The chemical biology of proteins, carbohydrates
  • The study of bioactive compounds
  • Natural products – isolation, synthesis and biosynthesis
  • Chemical genetics
  • The chemical biology of membranes
  • Methodologies for the discovery of therapeutic agents
  • Technological Advances Enabling Target Validation
  • chemical biology of chromatin regulation
  • translational drug discovery
  • Phenotypic screening, MOA and target deconvolution
  • Strategies to expand pharmacological modulation
  • Strategies to expand pharmacological modulation
  • Chemical proteomics and quantitative mass spectrometry in drug discovery
  • Case studies: Strategies for optimizing dmpk properties

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